Sirius Industrial-Grade Customized Peptide Synthesizer

Built for industrial peptide manufacturing, the PepAxis™-Sirius offers customizable large-scale reactors, precise metering pump transfer, and wide temperature control, ensuring stable, safe, and scalable production for peptide pharmaceutical applications.

PepAxis Sirius

The PepAxis™-Sirius (formerly 686) is a high-reliability, industrial-grade customized peptide synthesis system designed for large-scale peptide manufacturing. Featuring a modular and customizable architecture, the system supports reactor volumes ranging from 30 to 2000 L and synthesis scales of 0.3 mol and above, meeting the demands of continuous and large-batch industrial production.

The platform is equipped with a double-jacketed temperature-controlled reactor, an amino acid activation tank, and a piperidine buffer tank, all designed with sight-glass monitoring for real-time observation of pressure, temperature, and stirring conditions. This ensures full process visibility, controllability, and traceability throughout production.

The system supports multi-solvent position management and precise quantitative transfer via metering pumps. Combined with mechanical agitation and a wide temperature control range from –20 °C to 50 °C, it delivers stable reaction performance and excellent process reproducibility.

Certified with explosion-proof safety standards and equipped with automatic alarm mechanisms, the PepAxis™-Sirius is well suited for industrial-scale peptide pharmaceutical manufacturing, process scale-up, and customized synthesis services, providing a safe, efficient, and scalable peptide production solution.

Technical Parameters

Channels

1

Reactor

30~2000 L

Amino Acid Tank

1

Deprotection Tank

1

Synthesis Scale

≥ 0.3 mol

Temperature Control Method

Water/Ethylene Glycol

Solvent Stations

≤9

Reaction

304 Stainless Steel Lined with 316L Stainless Steel

Stirring Mode

Paddle stirring

Amino Acid Activation Tank

304 stainless steel with 316L stainless steel lining

Deprotection Buffer Tank

304 stainless steel with 316L stainless steel lining

Power Supply

220/380V

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